Transparent Labs Fat Burner Review: Is It Really Worth It?

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Physique Series is a fat-burning supplement manufactured by Transparent Labs. It contains a range of different ingredients, including caffeine, herbal extracts, and amino acids.

This is my #1 pick for the best fat-burning supplements.

In this article, I’m going to look at a couple of different things: the ingredients, dosages, and whether the price is actually justified by the Transparent Labs’ formula.

One important thing to keep in mind is that fat-burners do not work on their own. If you’ve come across a supplement that is promising mind-boggling results with no effort, then it’s likely that you’re seeing a marketing ploy designed to depart you from your money.

Fat-burners can be effective when combined with a proper diet and exercise, and they often contain plant extracts, vitamins, and minerals that help support weight and fat loss.

You might already know this, but there are no immediate shortcuts to a better body, and getting into shape requires patience and consistency, and you must have those two to follow a healthy and nutritious diet, as well as a workout plan. It’s important to point this out, especially for people that might want to purchase this supplement but also avoid working out.

Let’s see what this fat-burner by Transparent Labs is really about.

How Does Transparent Labs Fat Burner Work?

Transparent Labs PhysiqueSeries Fat Burner is a thermogenic fat-burning supplement that claims to work by providing you with two benefits: increasing your basal metabolic rate and preventing you from having potential cravings (or reducing your appetite). 

Put simply, this fat-burner revs up the amount of energy your body needs to carry out its various chemical processes, increasing the number of calories you spend. People who typically struggle to lose weight have a “slow” metabolism, and people with a “fast” metabolism can lose weight more easily because they’re capacitated to burn more calories.

This is achieved by ingredients such as Forslean, Green Tea Extract, and Synephrine which increase the body’s basal metabolic rate to levels that can’t be easily achieved by just following a highly nutritious diet.

Then you have ingredients like 5-HTP that manufacturers claim to be highly effective at suppressing appetite and hunger cravings. Combined with other ingredients, it should make your weight and fat loss process easier, but it’s only possible if you follow a restrictive diet and a solid calorie-burning training plan.

What Are The Ingredients?

Transparent Labs PhysiqueSeries Fat Burner contains 9 main active ingredients that Transparent Labs claims to have been chosen after careful scientific consideration.

The ingredients that have been picked to increase the basal metabolic rate and reduce your appetite are the following: Forslean, Green Tea, 5-HTP, L-Tyrosine, L-Theanine, Caffeine Anhydrous, White Willow, Cayenne Pepper, and Synephrine HCI.

fat burner ingredients

It’s important to mention that among these ingredients, some have, according to the manufacturer, the capacity to reduce mental and physical stress.

Let’s look at each individual ingredients and see if those claims are true. 


Forslean (or Coleus Forskohlii) is a herb used in traditional medicine that’s associated with the increase in testosterone production, as well as fat loss.

coleus plant

The core bioactive ingredient is forskolin, which studies suggest it increases the cellular levels of a molecule called cyclic adenosine monophosphate. This particular molecule is linked to augmented rates of fat loss and it can also increase the effects of other fat-burning compounds.

That being said, more research is required to fully confirm these benefits. Tests conducted with Forslean are often done outside the human body, in other words, they’re either done using a test tube or petri dish. Its effects may be somewhat different inside the body.

Still, even Forskolin is being researched for its testosterone-boosting and fat-burning effects, the preliminary evidence available seems to be very promising. Additionally, the dosage that is used in the aforementioned research is 500mg, which is the exact dose used by Transparent Labs.

Green Tea

Green tea contains water-soluble polyphenols called catechins which are essentially four molecules— with the most predominant and potent one being EGCG. 

green tea

It’s often suggested that green tea benefits almost every organ in the body. It’s cardioprotective, anti-obesity, anti-carcinogenic, neuroprotective, anti-diabetic, anti-atherogenic, liver protective, as well as beneficial for blood vessel health. However, these effects still remain under investigation.

While green tea may be beneficial for a number of different things, it may not be potent enough.

As far as fat-loss goes, the benefits of green tea on lipid oxidation and related fat-burning pathways are only achieved at high-doses. In fact, significant effects on humans are only relevant when you consume between 400-500mg EGCG per day. Transparent Labs seems to have accounted for this since each serving contains 400mg.


Sourced from Griffonia Simplicifolia, 5-HTP is the precursor to serotonin, which is a neurotransmitter considered to be responsible for our happiness. In this particular case, however, 5-HTP is not used in that regard, even though it may provide you with such benefit.


5-HTP can affect your weight loss through its appetite supressant qualities. According to the evidence available, 5-HTP supplementation does seem to be effective in appetite suppression in the higher dosage range, more specifically between 300-500mg.

Transparent Labs’ fat burner contains 300mg per serving, which is once again, compatible with the dose used by the researchers.


L-Tyrosine is the active form of tyrosine and is touted as a powerful anti-stress amino acid with several roles in the human body. It’s basically used to produce noradrenaline and dopamine, which reduce stress during exposure to acute stressors, which typically deplete noradrenaline.

Transparent Labs has decided to include L-Tyrosine because it can improve the outcome and experience during fat-loss. In other words, for most people, a process of transformation can be stress-inducing, and L-Tyrosine is an ingredient that can help cope.

The studies that have shown the most promise for its stress-reducing effects have used a dosage range of 100-150mg per kilogram of bodyweight. This means you’d have to take between 9-13.5g of L-Tyrosine if you weigh 200lb. Transparent Labs formula contains 300mg of L-tyrosine, which doesn’t seem to be compatible with what the studies use.

One thing to keep in mind, however, is that Transparent Labs’ fat burner contains different ingredients with anti-stress traits, namely 5-HTP and L-Theanine.


L-Theanine is a naturally occurring amino acid commonly found in green tea alongside EGCG. It appears to have a wide range of benefits, as it promotes relaxation without causing drowsiness.

Based on the somewhat preliminary evidence, L-Theanine does seem to be effective in reducing anxiety, stress, and provide you with a greater ability to relax. These effects have a positive impact on sleep quality due to deeper sleep, but it’s not necessarily effective against insomnia.

Interestingly, L-Theanine coupled with caffeine seems to be synergistic in promoting cognition and attention, an ingredient that Transparent Labs has also included in their formula.

Caffeine Anhydrous

Caffeine Anhydrous is basically the pure form of caffeine. It’s a powerful stimulant, and it can be used to improve physical strength and endurance. Habitual caffeine consumption is also associated with a reduced risk of Alzheimer’s, cirrhosis, and liver cancer.


At certain dosages, caffeine also appears to have fat-burning effects. Some studies suggest that caffeine can have an impact on fat oxidation, as well as provide users with natural thermogenic effects that can improve the rate at which calories are burned. Paired with its ability to increase physical strength and endurance (energy output), you can maximize the amount of workload and calories you burn in a single workout session.

Transparent Labs’ fat burner contains 240mg of Caffeine Anhydrous, which is an effective dose for increasing endurance (or anaerobic capacity), as well as other fat-burning benefits. An increase in physical strength seems to occur only at higher dosages of 500mg or more.

At the same time, it’s important to note that habitual caffeine use can increase your tolerance, which means not everyone will experience the same effects from a certain dose of caffeine.

White Willow

White Willow bark extract is the natural source of Salicin, a compound that is converted to salicylic acid in the body.

Transparent Labs claims (by pointing to specific studies), that Salicin can potentiate the thermogenic effects of synephrine (also present in the supplement) in dieting individuals.

However, while that may be true (according to the study), the amount of evidence available is insufficient to determine if that’s the case.

Cayenne Pepper

Cayenne Pepper contains capsaicin or capsaicinoids. This is a molecule that stimulates adrenaline receptors and TRPV1 to increase heat quickly. It’s believed to increase thermogenesis, which enables you to burn more calories than average, and it also improves lipolysis, which is your body’s ability to convert fat into energy.

cayenne pepper

This is a common ingredient you’ll find in fat-burning supplements, as it’s supported by over 90 clinical studies. One thing to note, however, is that you can build a tolerance to this ingredient.

Besides the aforementioned benefits, capsaicinoids have an effect on appetite. They help you eat less and feel fuller for longer, which is tremendously helpful for anyone wanting to lose weight.

Synephrine HCI

Synephrine is an alkaloid naturally present in citrus plants from the Rutaceae family.

It’s also a fat burner, but it’s not as potent as ephedrine, which is one of the four active components of the herb Ephedra. Akin to ephedrine, Synephrine induces fat loss by increasing the amount of fat available for fuel as well as by increasing heat expenditure.

These processes, as mentioned earlier, are called thermogenesis and lipolysis.

Transparent Labs’ fat burner contains 50mg of Synephrine, which is compatible with the recommended dosages found in studies.

Is Transparent Labs Fat Burner Effective?

Before you decide to purchase a fat-burning supplement, you should guarantee that you’re following a strict diet (in a caloric deficit) and that you’re working out consistently. Otherwise, if you just take the supplement, it’s impossible to reap any of its potentials and claimed benefits.

From what I’m able to perceive, this fat burner by Transparent Labs contains mostly evidence-backed ingredients (with the exception of White Willow, which has limited research), and seems to actually follow the dosages used in the research. The same dosages are responsible for generating the effects produced in the studies.

That is to say, by using the right dosages, Transparent Labs ensures that the ingredients used actually play a role in your body. And for that reason, I have to say that it’s an effective supplement, but only if you combine it with proper diet and exercise.

Are There Any Side Effects?

Most of the reviews (or reports) made by customers, the product doesn’t seem to provoke any unnatural side effects, other than what’s common through the intake of caffeine. By this, I mean increased heart rate and a “jittery” feeling caused by the energy increase. In the rarest of cases, a caffeinated supplement may also induce people with nausea.

That being said, Transparent Labs also offers a Stim-Free fat-burning formula for anyone that wishes to avoid caffeine.

One last important note before we move on — if you happen to be pregnant or nursing, do not take this supplement. And by all means, feel free to visit a physician before use.

How To Take Transparent Labs Fat Burner

According to the manufacturer, you should generally take one capsule, twice a day between meals. However, take one serving first thing in the morning to assess caffeine tolerance, and then, if you’re comfortable, increase the intake to two capsules a day.

If you find out that you’re sensitive to caffeine, avoid taking the supplement six hours before bedtime, otherwise you’ll have trouble falling asleep.

Should You Purchase Transparent Labs Fat Burner?

This fat burner by Transparent Labs is our #1 pick among many fat-burning supplements. If you take the time to check each ingredient, you’ll learn that some of them are only effective at certain dosages, which is typically the dosage practiced in the actual studies.

Some manufacturers, when creating supplements, don’t seem to account for that, so oftentimes you’ll find supplements with the correct ingredients but the dosages are just not potent enough to provide the user with the beneficial effects.

With this fat-burning formula it’s a different story, because 90% of the ingredients are associated with fat-loss and are delivered in the right amount.

Plus, one thing that I highly appreciate about Transparent Labs, is that they’re very transparent in their approach to manufacturing supplements. You won’t find “hidden” proprietary formulas, and you’re also not going to find any weird fillers or additives. Quite the contrary.

If you’re looking for an effective fat-burning formula, then I can comfortably say that Transparent Labs has created a legitimate fat burner that will help you burn fat. For $49 a bottle, you get 60 capsules, which is the equivalent of two capsules a day for two months, and by ordering over one bottle, you can take advantage of their bulk discount.

Editor’s note: The content on this website is meant to be informative in nature, but it should not be taken as medical advice. The content of our articles is not intended for use as diagnosis, prevention, and/or treatment of health problems. It’s always best to speak with your doctor or a certified medical professional before making any changes to your lifestyle, diet, or exercise routine, or trying a new supplement.

Alexandre Valente

Hey there! My name is Alex and I've been vegan for more than five years! I've set up this blog because I'm really passionate about veganism and living a more eco-conscious life. Hopefully, I can use this website as a channel to help you out on your own journey!

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