When we scan the ingredient lists on food labels, E385, or calcium disodium EDTA, often appears as a recurring character.
While its role in food preservation and stabilization is well-documented, its standing within vegan dietary guidelines is less clear.
Is E385 vegan? The simple answer is yes, as E385 is typically a synthetic compound that isn’t directly derived from animal sources. However, when we consider aspects such as the origin of raw materials and potential testing procedures, the issue becomes a bit more nuanced.
That’s why we’ll both be digging deeper into what E385 is, its role in the food industry, and the reasons why its vegan status is often debated.
What Exactly Is E385?

E385, also known as calcium disodium EDTA, is a special additive used in our food.
It’s best known for its chelating properties, which basically refers to its ability to bind with metal ions, a quality that helps prevent deterioration and protect the color, flavor, and texture of foods.
It’s also known as a sequestrant, in other words, it’s able to affect the stability and the general quality of food products.
Although I’m not an expert, the fact that calcium disodium EDTA is synthesized in a laboratory is well-documented. And based on what I’ve researched, its production process involves reacting ethylenediamine with sodium cyanide and formaldehyde, forming ethylenedinitrilotetraacetic acid, which is better known as EDTA.
This compound is then reacted with calcium hydroxide and sodium hydroxide, which results in the final product, calcium disodium EDTA.
E385 And How It’s Commonly Used
As you might know, E385 is a versatile food additive with a broad range of applications.
Its primary function is as a preservative that stabilizes the product – thus helping extend the shelf life of food and drink products by preventing the effects of oxidation, which can lead to changes in color, flavor, and overall quality.
For instance, you’ll commonly find E385 in canned and packaged foods because these are the types of products that need a longer shelf life.
These may include canned beans, pickled vegetables, sauces, and salad dressings.
Additionally, E385 is often found in carbonated drinks, as it helps prevent the breakdown and discoloration of vitamins and flavors in these beverages. Certain baked goods also use E385 to maintain their color and freshness over time.
Beyond the food industry, E385 also finds its way into cosmetics and pharmaceuticals.
In skincare products, it also plays the role of enhancing stability and increasing shelf life, while in pharmaceutical products, it assists in the delivery of certain medications.
Is E385 Really Vegan?
As I’ve mentioned, calcium disodium ethylenediaminetetraacetate is a synthetic compound made by reacting ethylenediamine, formaldehyde, and sodium cyanide, which forms the tetrasodium salt (which is then converted to calcium disodium salt).
The raw materials and the production process do not involve animal products or by-products, which means that E385 is fully vegan.
But of course, while the additive itself is vegan, the end product may not be, that’s why it’s important to always scan and verify, even if that might imply contacting the company or manufacturer to fully confirm.
Other Frequently Asked Questions
Yes, E385 is safe for consumption in the amounts typically used in food products.
In fact, that’s why you’ve got the ‘e’ letter before the numbers— because this additive has already been scrutinized by the European Food Safety Authority (EFSA) and was deemed safe for use.
However, like any food additive, it’s something that should be consumed in moderation to avoid potential health risks.
Yes, E385, is generally considered halal because it’s typically synthesized from chemical reactions, not from animal or plant sources.
What’s The Bottom Line?
Despite the complex discussions surrounding food additives, the information that I came across indicates that E385 is, indeed, a vegan-friendly ingredient.
But hey, don’t keep this information to yourself—spread the word and share it with friends that might be in doubt.